Inflammatory status in human hepatic cirrhosis

Hepatic Cirrhosis

TIhC 0CCLPTen1CC inI h1o0Spitall Within a conmparatively shiort space of time of touIr unuISula.l examllples of cirrhosis of tihe li\-er in-younil-chil(lren has le(d us to Iake this comlnlLI1liunictionl. Disorders of tihe liver in chil(lhoo(l ha\ve iii recent N'ears not attracted imiuchi attentioni in tihis country, and we feel that tlhe mere ventilation of the suLb)ject, thIough,0LI we mXVn ha...

[Hepatic cirrhosis].

Hepatic Cirrhosis

Changes in human hepatic metabolism in steatosis and cirrhosis

AIM To understand the underlying metabolic changes in human liver disease we have applied nuclear magnetic resonance (NMR) metabolomics analysis to human liver tissue. METHODS We have carried out pilot study using 1H-NMR to derive metabolomic signatures from human liver from patients with steatosis, nonalcoholic steatohepatitis (NASH) or alcohol-related liver damage (ARLD) to identify species...

Disappearance of hepatic parenchymal nerves in human liver cirrhosis.

The normal human liver receives a substantial autonomic innervation that is thought to subserve motor, metabolic, and sensory functions. In this study an antibody to a neural axoplasmic protein (PGP 9.5) was used to visualise autonomic nerves in tissue from normal, precirrhotic, and cirrhotic livers. Nerve fibres were readily identified in the parenchyma and portal tracts of normal livers, and ...